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All I know is that Scribes are going to make bank with those Contracts. All guides talks about them and everyone will want them. Better ride that money wave while we can. Other than that, Alchemy and Jewelcrafting are always safe bets with tradable and marketable goods. Engineers can get an item for followers to bring back more Azerite, ot sure how much of a headstart that's gonna give them. The rest of the professions honestly looks kinda lame since most of everything is BoP anyway.
Is it profitable when you compare the time spent farming the ore to what you could have farmed elsewhere? No, it's not even half as valuable, at least not on my realm. That of course changes if you're on a server whose AH can supply a chain of golem production at a reasonable price, but that just isn't the case for me. I wish it was, could be a nice little side gig.
Disagree with your comments on Sky Golem. You need about 4200 ghost iron ore make this. Ghost Iron ore turns into bars which are used for Jard's Power source, but you only need 300 bars for that. You also need living steel which is transmuted from triullium, which in turn is transmuted from ghost iron. If you have an transmute master you proc on average about 20 additional trillium bars, that's like 7000g in savings.
All of my gold came from everyone buying stuff at a really marked up price for instance BS 2h mace if it proced epic i was making at least 125k per one and i was making batchs of 10 to 15 it was like 25k for blue and 125k+ for epics at the time. And i was buying the ore for like 16g to 40g a pop so huge profit. Im still trying to figure out what im gunna do now to rebuild it will be a slow process now.