As always, I will monitor and update this guide as new information comes in. If I've gotten anything glaringly and completely wrong, just tell me with as much data as possible. The idea is to find the fastest possible leveling method, NOT to argue about how good or bad individuals are. If you have hard data, post it! If you have an idea, let the thread know so we can test it!
Heirlooms. At the bare minimum you make sure all the armor pieces upgraded to 110, since this is the lion's share of your experience increase. Neck and Ring upgrades are secondary, but still important due to being able to enchant them. Trinkets can't be enchanted, but you'll want them at max as well, if only to save time by not having to worry about replacing them as you level. 

Island expeditions require groups of three players to venture to islands with randomly spawned enemies and piles of AP. The island expedition ends once they collect a certain amount of AP, and they are granted about 300 AP as a reward — unfortunately, players don’t get any of the between 6,000 and 12,000 AP they collect during the expedition. These missions can take anywhere from three to 20 minutes, and never once offer any real challenge or depth.
Do quests and complete the story of your first chosen area before returning to your capital to scrap all of the equipment items you acquired. You should be around Level 113 by the time you complete your first area. Before selecting your second zone, head to your faction hub ship to acquire your introductory quests to the mission table and your champions. Complete this introduction and then pick up the quest to establish your first foothold in enemy territory.
-PvP- Completely broken for some classes and I mean broken going from both sides of the spectrum, from classes destroying everyone, to classes that can't even kill another player. It's fairly common for a weak class to lose to a powerful class even if the weak class outgears them by 50+ ilvls. That's how broken PvP is and Blizzard doesn't seem to know what to do to fix it other than do blanket damage nerfs/buffs as those are the only changes we've seen.
I personally wouldn't recommend Bloodmyst Isle. There's a ton of quests but a lot of those quests have absolutely horrible drop rates on their items. A lot of the quest mobs also have very slow and/or spread out spawns so if there's other people there you're gonna be waiting for respawns or spending a lot of time traveling between spawn areas quite a bit. Overall it's just an incredibly slow zone as far as EXP goes.
The Horde levels 50-60 guide has been rewritten and revamped.  My 1-60 Horde leveling guide is now completely updated for the 1.12 Drums of War patch.  As you can see it is about 15% larger than the 40-50 guide (single largest guide page yet).  There is also a lot of route changes.  I moved the entire Silithus section from level 55 to level 58, which allowed me to include a lot more quests for that zone.  There is also a lot of other improvement to the route, including adding a lot more quests into the guide, mostly from Moonglade, Silithus and Eastern Plaguelands.  This will make the final level 59 grind much shorter.
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For Alliance it's Lok'Modan, Redridge, Darkshore, Felwood, Stranglethorn (both parts), Plaguelands. Somewhere between 3 - 3.5 of these get you to 60 in like a 16 hours /played, if you queue for dungeons at the same time. I recommend dropping everything at 45 and going to Darkshore-Felwood if you didn't do them yet - they are literally the fastest levelling zones in the game right now, maybe only trumped by Silverpine.
Tiragarde Sound and Stormsong Valley are both fairly similar zones, but Stormsong is a little longer, meaning that you might not even have to finish it to hit 120. Tiragarde also comes with a bit of a warning. There are plenty of side quests to do in the zone after you finish the story quests. Don’t do them. It’s not worth the time or the experience you’ll get.
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